Dr Corrales was featured on Eye World Magazine, the Newsmagazine of the American Society of Catararct and Refractive Surgery, describing a novel corneal transplant for emergency and high risk situations. The new modality of corneal transplant holds the promise of having much less risk of rejection compared to a traditional corneal transplant.
Date published online: September 2015
|CORNEA||New transplantation tack
by Maxine Lipner EyeWorld Senior Contributing Writer
Operating microscope view of cornea with fungal keratitis and impending perforation,
which warrant action. However, when the patient’s immune state is heightened, traditional transplants can be compromised.
Slit lamp photograph of VisionGraft cornea with central epithelial defect. A dense cataract can also be noted.
Sterile graft helps ensure long-term success
For situations involving a high risk of graft rejection, VisionGraft sterile tissue (Tissue Banks International, Baltimore) is a stopgap measure ultimately preserving long-term results, according to Gustavo A. Corrales, MD, Vision Consultants and Surgeons, Falls Church, Va. One of the biggest advantages of this gamma-irradiated sterile tissue is that it shouldn’t cause sensitization of the immune system, Dr. Corrales explained, adding that this tissue is devoid of any living cells that could trigger an immune memory.
A temporary solution
On the other hand, in transplant cases where the immune system is not revved up, such as keratoconus, chances of graft survival are high. This is about 73% at 10 years versus an emergency situation such as a corneal melt, infectious keratitis or trauma, where graft survival may be down around 40%, Dr. Corrales said.
VisionGraft in action
Dr. Corrales cited a recent case involving an uncontrolled diabetic patient who was referred to him with a very advanced corneal ulcer. The problem had begun about a month earlier when some vegetation had gotten into the 50-year-old patient’s eye while he was mowing the lawn.
Editors’ note: Dr. Corrales has no financial interests related to this article.